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MINUCCI , Saverio

Last name: MINUCCI

First name: Saverio

2017 (v1)

Publication

Metadata-only

Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis

Trabanelli, Sara Chevalier, Mathieu F Martinez Usatorre, Amaia

Group 2 innate lymphoid cells (ILC2s) are involved in human diseases, such as allergy, atopic dermatitis and nasal polyposis, but their function in human cancer remains unclear. Here we show that, in acute promyelocytic leukaemia (APL), ILC2s are increased and hyper-activated through the interaction of CRTH2 and NKp30 with elevated...

Uploaded on: March 27, 2023