There is a growing interest in using brown algal extracts thanks to the bioactive substances they produce for adaptation to the marine benthic environment. We evaluated the anti-aging and photoprotective properties of two types of extracts (50%-ethanol and DMSO) obtained from different portions, i.e., apices and thalli, of the brown seaweed,...
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2023 (v1)PublicationUploaded on: February 4, 2024
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2022 (v1)Publication
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Uploaded on: February 14, 2024 -
2021 (v1)Publication
Alginate-based electrospun nanofibers prepared via electrospinning technique represent a class of materials with promising applications in the biomedical and pharmaceutical industries. However, to date, the effect of alginate molecular mass and block composition on the biological response of such systems remains to some extent unclear. As such,...
Uploaded on: March 27, 2023 -
2020 (v1)Publication
Inflammation and oxidative stress are part of the complex biological responses of body tissues to harmful stimuli. In recent years, due to the increased understanding that oxidative stress is implicated in several diseases, pharmaceutical industries have invested in the research and development of new antioxidant compounds, especially from...
Uploaded on: April 14, 2023 -
2024 (v1)Publication
Fibrous erionite is the only zeolite classified as Group 1 carcinogen by the International Agency for Research on Cancer (IARC). Carcinogenesis induced by erionite is thought to involve several factors as biopersistence, the iron role and cation exchange processes. To better understand these mechanisms, a detailed investigation at the micro...
Uploaded on: July 3, 2024 -
2019 (v1)Publication
Photobiomodulation relies on the transfer of energy from incident photons to a cell photoacceptor. For many years the concept of photobiomodulation and its outcome has been based upon a belief that the sole receptor within the cell was the mitochondrion. Recently, it has become apparent that there are other photoacceptors operating in different...
Uploaded on: April 14, 2023 -
2022 (v1)Publication
Alveolar macrophages are the first line of defence against detrimental inhaled stimuli. To date, no comparative data have been obtained on the inflammatory response induced by different carcinogenic mineral fibres in the three main macrophage phenotypes: M0 (non-activated), M1 (pro-inflammatory) and M2 (alternatively activated). To gain new...
Uploaded on: March 27, 2023 -
2022 (v1)Publication
Exposure to mineral fibres represents a serious occupational and environmental hazard, since it leads to chronic lung inflammation with the subsequent emergence of fibrotic pulmonary diseases, pneumoconiosis and various types of malignancies. This happens mainly by inhalation, leading to the localization of the mineral fibers in the lung...
Uploaded on: July 5, 2024 -
2022 (v1)Publication
The health hazard posed by asbestos exposure may also concern other minerals with an asbestos-like crystalline habit. One of these potentially hazardous minerals is fibrous glaucophane which can occur with a fibrous habit similar to regulated amphibole asbestos minerals. Fibrous glaucophane is an important component of the blueschist rocks of...
Uploaded on: July 4, 2024 -
2022 (v1)Publication
In chrysotile, the most commercialized asbestos, Fe and other toxic metals are worth considering in its pathogenicity (Gualtieri et al., 2019); in fact, large amounts of Fe (>1000 ppm) and trace metals (Cr, Ni, Co, Mn, ...) are also intimately associated with the raw material. Since both Fe and trace metals are usually isomorphous substituent...
Uploaded on: July 4, 2024 -
2021 (v1)Publication
Today, despite considerable efforts undertaken by the scientific community, the mechanisms of carcinogenesis of mineral fibres remain poorly understood. A crucial role in disclosing the mechanisms of action of mineral fibres is played by in vitro and in vivo models. Such models require experimental design based on negative and positive...
Uploaded on: March 27, 2023 -
2022 (v1)Publication
Inhalation of mineral fibres is associated with the onset of an inflammatory activity in the lungs and the pleura responsible for the development of fatal malignancies. It is known that cell damage is a necessary step for triggering the inflammatory response. However, the mechanisms by which mineral fibres exert cytotoxic activity are not fully...
Uploaded on: April 14, 2023 -
2022 (v1)Publication
In chrysotile, the most commercialized asbestos species, Fe and other metals are worth considering in its potential toxicity (Gualtieri et al., 2019); in fact, large amounts of Fe (>1000 ppm) and trace metals (Cr, Ni, Co, Mn, etc.) are also intimately associated with the raw material. Since both Fe and trace metals are usually isomorphous...
Uploaded on: July 5, 2024 -
2023 (v1)Publication
Chrysotile is a natural hydrous layer silicate that belongs to the serpentine group. Because of its unique asbestiform shape and outstanding physical-chemical properties, chrysotile is still nowadays the most used commercial mineral fibre in the world. This occurs despite the mineral has been classified as a Group 1 carcinogen by the...
Uploaded on: July 5, 2024