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MISRAHI , Micheline

Last name: MISRAHI

First name: Micheline

February 2018 (v1)

Journal article

Metadata-only

A common African variant of human connexin 37 is associated with Caucasian primary ovarian insufficiency and has a deleterious effect in vitro

Bachelot, Anne Gilleron, Jérôme Meduri, Geri

Folliculogenesis requires communication between granulosa cells and oocytes, mediated by connexin-based gap junctions. Connexin 37 (Cx37)-deficient female mice are infertile. The present study assessed Cx37 deficiency in patients with primary ovarian insufficiency (POI). A candidate gene study was performed in patients and controls from the...

Uploaded on: March 26, 2023
December 2021 (v1)

Journal article

Metadata-only

Position statement on the diagnosis and management of premature/primary ovarian insufficiency (except Turner Syndrome)

Christin-Maitre, Sophie Givony, Maria Albarel, Frédérique

Premature ovarian insufficiency (POI) is a rare pathology affecting 1-2% of under-40 year-old women, 1 in 1000 under-30 year-olds and 1 in 10,000 under-20 year-olds. There are multiple etiologies, which can be classified as primary (chromosomal, genetic, auto-immune) and secondary or iatrogenic (surgical, or secondary to chemotherapy and/or...

Uploaded on: December 3, 2022