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MOLICA , Filippo

Last name: MOLICA

First name: Filippo

2020 (v1)

Publication

Metadata-only

A Genetic Polymorphism in the Pannexin1 Gene Predisposes for The Development of Endothelial Dysfunction with Increasing BMI

Molica, Filippo Quercioli, Alessandra Montecucco, Fabrizio

Endothelial dysfunction worsens when body mass index (BMI) increases. Pannexin1 (Panx1) ATP release channels regulate endothelial function and lipid homeostasis in mice. We investigated whether the Panx1-400A>C single nucleotide polymorphism (SNP), encoding for a gain-of-function channel, associates with endothelial dysfunction in non-obese and...

Uploaded on: April 14, 2023