MONDINI G

Twenty-two patients with recurrent melanoma of the limbs,underwent Hyperthermic Antiblastic Perfusion (HAP). HAP lasted 60 min,with maximal local temperature of 40.5-42 degrees C and melphalan 10 mg/L limb volume as antiblastic agent. Fourteen patients had in-transit metastases and 8 local recurrences. Regional nodes were involved in 6...