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2005 (v1)PublicationUploaded on: March 31, 2023
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2005 (v1)Publication
Background: Imatinib mesylate (STI-571, Gleevec) a small molecule tyrosine kinase inhibitor directed against the enzymatic domain of KIT protein, was recently found to produce dramatic clinical responses as monotherapy for metastatic GISTs. However, imatinib resistance can occur determining treatment failure. The present study was performed to...
Uploaded on: April 14, 2023 -
2003 (v1)Publication
BACKGROUND: Previous studies showed that the subtype 2 of somatostatin receptors (sstr2) is generally expressed by soft tissue sarcomas. MATERIALS AND METHODS: Using reverse transcription-polymerase chain reaction (RT-PCR), the present study evaluated the expression of sstr mRNA in 31 human intermediate and malignant soft tissue tumors. In 8...
Uploaded on: April 14, 2023