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MONTRREAL , Laura

Last name: MONTRREAL

First name: Laura

April 18, 2023 (v1)

Publication

Metadata-only

Mendelian randomisation confirms the role of Y-chromosome loss in Alzheimer's disease aetiopathogenesis in men

García-González, Pablo Rojas, Itziar de Moreno-Grau, Sonia

Mosaic loss of chromosome Y (mLOY) is a common ageing-related somatic event and has been previously associated with Alzheimer's disease (AD). However, mLOY estimation from genotype microarray data only reflects the mLOY degree of subjects at the moment of DNA sampling. Therefore, mLOY phenotype associations with AD can be severely...

Uploaded on: April 19, 2023
September 19, 2022 (v1)

Publication

Metadata-only

Genomic characterization of host factors related to SARS-CoV-2 infection in people with dementia and control populations: the GR@ACE/DEGESCO study

Rojas, Itziar de Hernández, Isabel Montrreal, Laura

Emerging studies have suggested several chromosomal regions as potential host genetic factors involved in the susceptibility to SARS-CoV-2 infection and disease outcome. We nested a COVID-19 genome-wide association study using the GR@ACE/DEGESCO study, searching for susceptibility factors associated with COVID-19 disease. To this end, we...

Uploaded on: December 4, 2022