MOORE , Stephen

This paper is concerned with the construction of graded meshes for approximating so-called singular solutions of elliptic boundary value problems by means of multipatch discontinuous Galerkin Isogeo-metric Analysis schemes. Such solutions appear, for instance, in domains with re-entrant corners on the boundary of the computational domain, in...

Isogeometric analysis (IGA) is a recently developed simulationmethod that allows integration of finite element analysis (FEA)with conventional computer-aided design (CAD) software [1,3]. This goal requires new software design strategies, in order toenable the use of CAD data in the analysis pipeline. To this end, we have initiated G+SMO...

Pulmonary arterial hypertension (PAH) is a destructive disease of the pulmonary vasculature often leading to right heart failure and death. Current therapeutic intervention strategies only slow disease progression. The role of aberrant hypoxia-inducible factor (HIF)2α stability and function in the initiation and development of pulmonary...