MORA CASTAÑO , Gloria

En los últimos 100 años, la esperanza de vida ha aumentado, por tanto, hay un envejecimiento de la población que repercute en el incremento de la prevalencia de las enfermedades neurodegenerativas, entre ellas la Degenarción Macular Asociada a la Edad (DMAE). Estas enfermedades son proteinopatías pues los mecanismos que mantienen la...

Los sistemas de liberación prolongada (SLP) pretenden conseguir que el fármaco se libere en un lugar adecuado del organismo, asegurar una buena absorción y/o modificar la velocidad de liberación respecto a los sistemas convencionales. De esta manera aumentaría la eficacia del tratamiento terapéutico al mejorar el cumplimiento posológico,...

Three-dimensional printing (3DP) technology enables an important improvement in the design of new drug delivery systems, such as gastroretentive floating tablets. These systems show a better temporal and spatial control of the drug release and can be customized based on individual therapeutic needs. The aim of this work was to prepare 3DP...

Three-dimensional (3D) printing technology enables the design of new drug delivery systems for personalised medicine. Polymers that can be molten are needed to obtain extruded filaments for Fused Deposition Modelling (FDM), one of the most frequently employed techniques for 3D printing. The aim of this work was to evaluate the extrusion process...

A biodegradable copolyester, poly(butylene succinate-co-ε-caprolactone) (PBS_CL), was used for first time as an excipient for pharmaceutical dosage forms using direct compression and hot processing techniques (ultrasound-assisted compression (USAC) and hot melt extrusion (HME)). Robust binary systems were achieved with hot processing...

The use of 3D printing technology in the manufacturing of drug delivery systems has expanded and benefit of a customized care. The ability to create tailor-made structures filled with drugs/delivery systems with suitable drug dosage is especially appealing in the field of nanomedicine. In this work, chitosan-based polymeric micelles loaded with...