Human group IIA-secreted phospholipase A(2) (sPLA(2)-IIA) is a bactericidal molecule important for the innate immune defense against Gram-positive bacteria. In this study, we analyzed its role in the host defense against Streptococcus pyogenes, a major human pathogen, and demonstrated that this bacterium has evolved a previously unidentified...
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December 15, 2011 (v1)Journal articleUploaded on: December 3, 2022
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December 15, 2013 (v1)Journal article
Group B streptococcus (GBS) is a leading neonatal pathogen and a growing cause of invasive disease in the elderly, with clinical manifestations such as pneumonia and sepsis. Despite its clinical importance, little is known about innate immunity against GBS in humans. Here, we analyze the role of human group IIA secreted phospholipase A2...
Uploaded on: December 4, 2022 -
October 15, 2018 (v1)Journal article
International audience
Uploaded on: December 4, 2022