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April 29, 2020 (v1)PublicationUploaded on: December 4, 2022
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February 27, 2017 (v1)Publication
The inclusion complexes of cyclodextrins with drugs where the changes brought to the physical, chemical and biological properties of the guest molecules endow the final product with considerable pharmaceutical potential. The complexation properties of β and γ-cyclodextrins with a variety of drugs widely used in clinical practice such as...
Uploaded on: March 27, 2023 -
April 7, 2017 (v1)Publication
Solubilisation of six polycyclic aromatic hydrocarbons (PAHs) (acenaphthene, anthracene, fluoranthene, fluorene, phenanthrene and pyrene) by three synthetic cyclodextrins (CDs) (2-hydroxypropyl-β-CD, hydroxypropyl-γ-CD and ramdomly methylated-β-CD) was investigated in order to select the CD which presents the greatest increase in solubility and...
Uploaded on: December 4, 2022 -
January 5, 2022 (v1)Publication
The purpose of this study was to design, for the first time, a co-loaded liposomal formulation (CLL) for treatment of glaucoma including timolol maleate (TM) in the lipid bilayer and acetazolamide (Acz)-(2-hydroxy)propyl β-cyclodextrin (HPβCD) complexes (AczHP) solubilized in the aqueous core of liposomes. Formulations with TM (TM-L) and AczHP...
Uploaded on: December 4, 2022