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MURIANA , Francisco J. G.

Last name: MURIANA

First name: Francisco J. G.

January 25, 2023 (v1)

Publication

Metadata-only

Exogenous fatty acids and niacin on acute prostaglandin D-2 production in human myeloid cells

Montserrat de la Paz, Sergio Bermúdez Pulgarín, Beatriz López Martín, Sergio

Niacin activates HCA2 receptor that results in the release of PGD2. However, little is known on PGD2-producing cells and the role of fatty acids. Notably M-CSF macrophages exhibited a timely dependent PGD2 production upon niacin challenge. Short pretreatment of M-CSF macrophages with autologous postprandial TRLs induced the down-regulation of...

Uploaded on: March 1, 2023
March 23, 2022 (v1)

Publication

Metadata-only

Oleuropein and its peracetylated derivative negatively regulate osteoclastogenesis by controlling the expression of genes involved in osteoclast differentiation and function

Rosillo Ramírez, María de los Ángeles Montserrat de la Paz, Sergio Abia González, María del Rocío

During chronic inflammation, macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor-κB ligand (RANKL) have well established effects on gene networks that stimulate osteoclastogenesis, which is the culprit of several bone diseases. In this study, we investigated the anti-osteoclastogenic effects in vitro of...

Uploaded on: March 1, 2023