2005 (v1)
Publication
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Uploaded on: March 27, 2023
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Last name: NALDINI A
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The main aim of this study was to enhance the soly. of pyrazolo[3,4-d]pyrimidines 1-8 able to strongly inhibit Src and Abl tyrosine kinase phosphorylation in cell-free assays and to significantly reduce leukemic and osteosarcoma cell lines growth, but characterized by very low soly. in aq. media. Their water soly. was improved between 100 and...