NARDONE R.

Background Some guidelines or expert consensus indicate that intravenous (IV) lorazepam (LZP) is preferable to IV diazepam (DZP) for initial treatment of convulsive status epilepticus (SE). We aimed to critically assess all the available data on efficacy and tolerability of IV LZP compared with IV DZP as first-line treatment of convulsive SE....

Jean-Martin Charcot (1825–1893) laid the foundations of modern neurology. The lectures he gave at La Salpêtrière Hospital in Paris attracted a large number of visitors from all over the world. Some of them transcribed these clinical lessons, translating and publishing them when returning home. This article discusses the contribution of some...

Objective: To evaluate the potential impact of concomitant clobazam (CLB) use on the efficacy of cannabidiol (CBD) treatment in patients with Dravet syndrome and Lennox-Gastaut syndrome using meta-analytical techniques. Methods: We searched for randomized, placebo-controlled, single- or double-blinded trials. The proportion of patients who...