NAVARRO PANDO , José Manuel

Se estudia la masa ósea en 134 mujeres premenopáusicas, de edades comprendidas entre los 40 y 50 años. El 80% presentaron valores de D.M.O. inferiores a los normales, con una elevada proporción, el 22%, situados por debajo del umbral de fractura fácil, resultados que no coinciden con lo aceptado hasta ahora. El estado de la masa ósea en la...

Internet of Medical Things (IoMT) is a technological concept applied in healthcare contexts to achieve the digital interconnection of everyday objects with the Internet in order to make life easier for people. IoMT can help monitor, inform and notify not only caregivers, but provide healthcare providers with actual data to identify issues...

Fibromyalgia (FM) is a common chronic pain syndrome accompanied by a myriad of variable physical and psychopathological symptoms such as fatigue, muscle stiffness, sleep disorders, morning tiredness, cognitive complaints, as well as depression and anxiety 1. Despite the fact that it affects up to 5% of the general population worldwide, its...

Major depressive disorder (MDD) is a psychiatric disease characterized by important mood changes accompanied by other symptoms such as low self-esteem, anhedonia, sleep disorder, cognition, and eating and which is estimated to be the second major illness measured by social and economic burden by 2020.1 MDD has prevalence about 10% of the...

The pandemic suffered in 2020 following the appearance of the SARS CoV-2 virus has marked a radical change in the way in which the basic pillars of international, and more specifically Spanish, society are understood. The existing social and economic model has had to adapt abruptly and urgently to the reality of what has happened. The impact...

En los últimos años, los avances en las Tecnologías de la Información y la Comunicación (TIC) las han hecho imprescindibles en nuestra sociedad, especialmente en el funcionamiento de muchas organizaciones. Un ejemplo sería el impacto que han tenido y tienen en la medicina. Son fundamentales para mejorar la calidad, eficacia y eficiencia de los...

Inflammation is a hallmark of aging and accelerated aging syndromes such as Hutchinson–Gilford progeria syndrome (HGPS). In this study, we present evidence of increased expression of the components of the NLRP3 inflammasome pathway in HGPS skin fibroblasts, an outcome that was associated with morphological changes of the nuclei of the cells....

Inflammation is a hallmark of aging and is negatively affecting female fertility. In this study, we evaluate the role of the NLRP3 inflammasome in ovarian aging and female fertility. Age-dependent increased expression of NLRP3 in the ovary was observed in WT mice during reproductive aging. High expression of NLRP3, caspase-1, and IL-1β was also...

Conventional cardiovascular risk factors (CVRFs) are accepted to identify asymptomatic individuals with high risk of acute myocardial infarction (AMI). However, AMI affects many patients previously classified at low risk. New biomarkers are needed to improve risk prediction. We propose to evaluate the NLRP3–inflammasome complex as a potential...