N

J

NOËL , Josette

Last name: NOËL

First name: Josette

July 2008 (v1)

Journal article

Metadata-only

Regulation of Na+/H+ exchanger 1 allosteric balance by its localization in cholesterol- and caveolin-rich membrane microdomains.

Tekpli, Xavier Huc, Laurence Lacroix, Jérôme

The Na+/H+ exchanger 1, which plays an essential role in intracellular pH regulation in most tissues, is also known to be a key actor in both proliferative and apoptotic processes. Its activation by H+ is best described by the Monod-Wyman-Changeux model: the dimeric NHE-1 oscillates between a low and a high affinity conformation, the balance...

Uploaded on: December 4, 2022