International audience
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September 2016 (v1)Journal articleUploaded on: December 4, 2022
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August 2018 (v1)Journal article
International audience
Uploaded on: December 4, 2022 -
May 21, 2016 (v1)Journal article
Human brown adipocytes are able to burn fat and glucose and are now considered as a potential strategy to treat obesity, type 2 diabetes and metabolic disorders. Besides their thermogenic function, brown adipocytes are able to secrete adipokines. One of these is visfatin, a nicotinamide phosphoribosyltransferase involved in NAD synthesis, known...
Uploaded on: December 4, 2022 -
August 2016 (v1)Journal article
International audience
Uploaded on: December 4, 2022 -
January 2018 (v1)Journal article
International audience
Uploaded on: December 4, 2022 -
September 2023 (v1)Journal article
Highlights d Cold induces a change in serum metabolites that are essential to NAD + metabolism d Circulatory NAM, tryptophan, and kynurenine are linked to BAT activation during cold d NAD + biosynthesis pathways are upregulated in BAT compared with WAT d BAT NAD + biosynthesis is related to whole-body metabolic health
Uploaded on: November 27, 2023 -
2021 (v1)Journal article
Activation of thermogenic brown and beige adipocytes is considered as a strategy to improve metabolic control. Here, we identify GPR180 as a receptor regulating brown and beige adipocyte function and whole-body glucose homeostasis, whose expression in humans is associated with improved metabolic control. We demonstrate that GPR180 is not a GPCR...
Uploaded on: December 3, 2022