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O

F

ONOFRI , Franco

Last name: ONOFRI

First name: Franco

Email: franco.onofri@unige.it

Institution: UNIGE

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    Recent uploads

  • 1999 (v1)
    Publication
    Metadata-only
    Protein-protein interactions and protein modules in the control of neurotransmitter release
    BENFENATI, FABIO ONOFRI, FRANCO GIOVEDI', SILVIA

    No description

    Uploaded on: April 14, 2023
  • 2007 (v1)
    Publication
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    Influence of synapsin I on synaptic vesicles: an analysis by force-volume-mode of the atomic force microscope and dynamic light scattering
    AWIZIO AK ONOFRI, FRANCO BENFENATI, FABIO

    No description

    Uploaded on: April 14, 2023
  • 2017 (v1)
    Publication
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    Synapsins Are Downstream Players of the BDNF-Mediated Axonal Growth
    MARTE, ANTONELLA Messa, Mirko BENFENATI, FABIO

    Synapsins (Syns) are synaptic vesicle-associated phosphoproteins involved in neuronal development and neurotransmitter release. While Syns are implicated in the regulation of brain-derived neurotrophic factor (BDNF)-induced neurotransmitter release, their role in the BDNF developmental effects has not been fully elucidated. By using primary...

    Uploaded on: April 14, 2023
  • 1996 (v1)
    Publication
    Metadata-only
    Biochemical and functional characterization of the synaptic vesicle-associated form of Ca2+/calmodulin-dependent protein kinase II.
    BENFENATI, FABIO ONOFRI, FRANCO CZERNIK A. J.

    No description

    Uploaded on: December 5, 2022
  • 2009 (v1)
    Publication
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    ERK activation in axonal varicosities modulates presynaptic plasticity in the CA3 region of the hippocampus through synapsin I.
    VARA H ONOFRI, FRANCO BENFENATI, FABIO

    Activity-dependent changes in the strength of synaptic connections in the hippocampus are central for cognitive processes such as learning and memory storage. In this study, we reveal an activity-dependent presynaptic mechanism that is related to the modulation of synaptic plasticity. In acute mouse hippocampal slices, high-frequency...

    Uploaded on: May 13, 2023
  • 2013 (v1)
    Publication
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    Biochimica del Sistema Nervoso
    BENFENATI, FABIO CORRADI, ANNA MARGHERITA GIOVEDI', SILVIA

    No description

    Uploaded on: April 14, 2023
  • 2004 (v1)
    Publication
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    S100A1 codistributes with synapsin I in discrete brain areas and inhibits the F-actin-bundling activity of synapsin I
    BENFENATI, FABIO FERRARI R. ONOFRI, FRANCO

    No description

    Uploaded on: April 14, 2023
  • 2010 (v1)
    Publication
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    Binding of protein kinase inhibitors to synapsin I inferred from pair-wise binding site similarity measurements.
    DEFRANCHI E SCHALON C MESSA M

    Predicting off-targets by computational methods is getting increasing importance in early drug discovery stages. We herewith present a computational method based on binding site three-dimensional comparisons, which prompted us to investigate the cross-reaction of protein kinase inhibitors with synapsin I, an ATP-binding protein...

    Uploaded on: April 14, 2023
  • 1993 (v1)
    Publication
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    Interactions of synapsin I with phospholipids: possible role in synaptic vesicle clustering and in the maintenance of bilayer structures.
    BENFENATI, FABIO ONOFRI, FRANCO VALTORTA F.

    No description

    Uploaded on: April 14, 2023
  • 2010 (v1)
    Publication
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    Tyrosine phosphorylation of synapsin I by Src regulates synaptic-vesicle trafficking
    MESSA M CONGIA S DEFRANCHI E

    No description

    Uploaded on: April 14, 2023
  • 2003 (v1)
    Publication
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    Phosphatidylinositol 4-kinase type IIα is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles.
    GUO J WENK M. R PELLEGRINI L

    No description

    Uploaded on: March 31, 2023
  • 2015 (v1)
    Publication
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    Synaptic mechanisms underlying the excessive and precocious glutamate release in the spinal cord of sod1g93a mice.
    BONIFACINO, TIZIANA MILANESE, MARCO Musazzi, L

    No description

    Uploaded on: April 14, 2023
  • 2008 (v1)
    Publication
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    Synapsin-I- and synapsin-II-null mice display an increased age-dependent cognitive impairment
    CORRADI, ANNA MARGHERITA ONOFRI, FRANCO BENFENATI, FABIO

    Synapsin I (SynI) and synapsin II (SynII) are major synaptic vesicle (SV) proteins that function in the regulation of the availability of SVs for release in mature neurons. SynI and SynII show a high level of sequence similarity and share many functions in vivo, although distinct physiological roles for the two proteins have been proposed. Both...

    Uploaded on: April 14, 2023
  • 1995 (v1)
    Publication
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    Phosphorylation of VAMP/synaptobrevin in synaptic vesicles by endogenous protein kinases.
    NIELANDER H. B. VALTORTA F. SCHIAVO G.

    No description

    Uploaded on: December 5, 2022
  • 2003 (v1)
    Publication
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    Specific interactions of neuronal focal adhesion kinase isoforms with Src kinases and amphiphysin
    MESSINA S ONOFRI, FRANCO BONGIORNO BORBONE L

    No description

    Uploaded on: April 14, 2023
  • 1996 (v1)
    Publication
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    Synapsin-like molecules in Aplysia Punctata and Helix Pomatia: identification and distribution in the nervous system and during the formation of synaptic contacts in vitro.
    CIBELLI G. GHIRARDI M. CASADIO A.

    No description

    Uploaded on: December 5, 2022
  • 2012 (v1)
    Publication
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    LRRK2 interacts with synaptic vesicles at the presynaptic level
    MARTE, ANTONELLA ONOFRI, FRANCO Elisa Belluzzi

    No description

    Uploaded on: April 14, 2023
  • 2011 (v1)
    Publication
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    GLUTAMATE NEUROTRANSMISSION IS MODIFIED IN THE SOD1/G93A MOUSE MODEL OF ALS
    USAI, CESARE MILANESE, MARCO BONIFACINO, TIZIANA

    No description

    Uploaded on: April 14, 2023
  • 2013 (v1)
    Publication
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    G93A mutated SOD1-linked murine ALS produces abnormal exocytotic release of glutamate
    USAI, CESARE MILANESE, MARCO BONIFACINO, TIZIANA

    No description

    Uploaded on: April 14, 2023
  • 2014 (v1)
    Publication
    Metadata-only
    Functional role of ATP binding to synapsin I in synaptic vesicle trafficking and release dynamics.
    ORLANDO, MARTA LIGNANI, GABRIELE FASSIO, ANNA

    Synapsins (Syns) are synaptic vesicle (SV)-associated proteins involved in the regulation of synaptic transmission and plasticity, which display a highly conserved ATP binding site in the central C-domain, whose functional role is unknown. Using molecular dynamics simulations, we demonstrated that ATP binding to SynI is mediated by a...

    Uploaded on: April 14, 2023
  • 2011 (v1)
    Publication
    Metadata-only
    Abnormal exocytotic release of glutamate in a mouse model of amyotrophic lateral sclerosis
    USAI, CESARE MILANESE, MARCO BONIFACINO, TIZIANA

    No description

    Uploaded on: April 14, 2023
  • 2000 (v1)
    Publication
    Metadata-only
    The inhibitory effects of interleukin-6 on synaptic plasticity in the rat hippocampus are associated with an inhibition of mitogen-activated protein kinase ERK.
    TANCREDI V D'ANTUONO M CAFÈ C

    No description

    Uploaded on: December 5, 2022
  • 2011 (v1)
    Publication
    Metadata-only
    Abnormal glutamate release in a mouse model of amyotrophic lateral sclerosis
    MILANESE, MARCO BONIFACINO, TIZIANA ONOFRI, FRANCO

    No description

    Uploaded on: April 14, 2023

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