February 6, 2024 (v1)
Publication
We have used the Cu(i)-catalyzed azide-alkyne Huisgen cycloaddition reaction to obtain two families of bivalent heterodimers where tacrine is connected to an azasugar or iminosugar, respectively,vialinkers of variable length. The heterodimers were investigated as cholinesterase inhibitors and it was found that their activity increased with the...
Uploaded on: February 11, 2024