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OSLUND , Rob

Last name: OSLUND

First name: Rob

May 1, 2010 (v1)

Journal article

Metadata-only

Production of vascular endothelial growth factors from human lung macrophages induced by group IIA and group X secreted phospholipases A2.

Granata, Francescopaolo Frattini, Annunziata Loffredo, Stefania

Angiogenesis and lymphangiogenesis mediated by vascular endothelial growth factors (VEGFs) are main features of chronic inflammation and tumors. Secreted phospholipases A(2) (sPLA(2)s) are overexpressed in inflammatory lung diseases and cancer and they activate inflammatory cells by enzymatic and receptor-mediated mechanisms. We investigated...

Uploaded on: December 3, 2022
February 2009 (v1)

Journal article

Metadata-only

Expression of phospholipases A2 in primary human lung macrophages: role of cytosolic phospholipase A2-alpha in arachidonic acid release and platelet activating factor synthesis.

Giannattasio, Giorgio Lai, Ying Granata, Francescopaolo

Macrophages are a major source of lipid mediators in the human lung. Expression and contribution of cytosolic (cPLA(2)) and secreted phospholipases A(2) (sPLA(2)) to the generation of lipid mediators in human macrophages are unclear. We investigated the expression and role of different PLA(2)s in the production of lipid mediators in primary...

Uploaded on: December 3, 2022