PÉREZ DE CAMINO CANTOS , Dolores

El género Phycomyces (Mucoromycotina, Mucorales) ha sido revisado analizando 96 estirpes recibidas de colecciones o recién aisladas en diferentes entornos. La morfología, la sexualidad, las secuencias de ADN y la estructura de las poblaciones identifican sin ambigüedad al género y lo distinguen del resto de los Mucorales. El tamaño de las...

R loops are nucleic acid structures comprising an DNA-RNA hybrid and a displaced single-stranded DNA. These structures may occur transiently during transcription, playing essential biological functions. However, persistent R loops may become pathological as they are important drivers of genome instability and have been associated with human...

Transcription is an essential process of DNA metabolism, yet it makes DNA more susceptible to DNA damage. THSC/TREX-2 is a conserved eukaryotic protein complex with a key role in mRNP biogenesis and maturation that prevents genome instability. One source of such instability is linked to transcription as shown in yeast and human cells, but the...