P

H

PÉREZ-SÁNCHEZ , Horacio

Last name: PÉREZ-SÁNCHEZ

First name: Horacio

February 22, 2023 (v1)

Publication

Metadata-only

Piperazine-derived small molecules as potential Flaviviridae NS3 protease inhibitors. In vitro antiviral activity evaluation against Zika and Dengue viruses

García Lozano, María del Rosario Dragoni, Filippo Gallego, Paloma

Since 2011 Direct Acting antivirals (DAAs) drugs targeting different non-structural (NS) viral proteins (NS3, NS5A or NS5B inhibitors) have been approved for clinical use in HCV therapies. However, currently there are not licensed therapeutics to treat Flavivirus infections and the only licensed DENV vaccine, Dengvaxia, is restricted to...

Uploaded on: March 1, 2023