1981 (v1)
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P
S
PARODI , Silvio
Last name: PARODI
First name: Silvio
Institution: UNIGE
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1997 (v1)Publication
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1993 (v1)Publication
For a database of 826 chemicals tested for carcinogenicity, we fragmented the structural formula of the chemicals into all possible contiguous-atom fragments with size between two and eight (nonhydrogen) atoms. The fragmentation was obtained using a new software program based on graph theory. We used 80% of the chemicals as a training set and...
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1994 (v1)Publication
A decision support system which analyses the topological properties of molecular fragments to predict carcinogenic activity of organic chemical compounds is described in this work. Such a system, given a set of organic compound of known carcinogenic activity, detects the submolecular structures that could interact with biological sites involved...
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2008 (v1)Publication
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2003 (v1)Publication
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2004 (v1)Publication
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1999 (v1)Publication
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1978 (v1)Publication
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1980 (v1)Publication
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2001 (v1)Publication
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1996 (v1)Publication
We have applied a new software program, based on graph theory and developed by our group, to predict mutagenicity in Salmonella. The software analyzes, as information in input, the structural formula and the biological activities of a relatively large database of chemicals to generate any possible molecular fragment with size ranging from two...
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1995 (v1)Publication
Seven ovarian and one cervical human cancer cell lines were examined far their sensitivity or resistance to tumor necrosis factor, to three topoisomerase II inhibitors and to cisplatin. Only one line exhibited the multidrug-resistance phenotype and another one an 'atypical'-MDR phenotype. The combination of TNF and topoisomerase-II inhibitors...
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2012 (v1)Publication
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2012 (v1)Publication
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1981 (v1)Publication
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2011 (v1)Publication
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2001 (v1)Publication
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2006 (v1)Publication
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2003 (v1)Publication
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2013 (v1)Publication
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