1996 (v1)
Publication
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Uploaded on: April 14, 2023
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1995 (v1)Publication
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Uploaded on: December 5, 2022 -
2008 (v1)Publication
Human mesenchymal stem cells (MSC) are immunosoppressive and poorly immunogenic but may act as antigen-presenting cells (APC) for CD4_ T-cell responses; here we have investigated their ability to serve as APC for in vitro CD8T-cell responses. MSC pulsed with peptides from viral antigens evoked interferon (IFN)- and Granzyme B secretion in...
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2002 (v1)Publication
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2000 (v1)Publication
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Uploaded on: December 5, 2022 -
2008 (v1)Publication
Mesenchymal stem cells (MSC) establish close interactions with bone marrow sinusoids in a putative perivascular niche. These vessels contain a large storage pool of mature nonproliferating neutrophils. Here, we have investigated the effects of human bone marrow MSC on neutrophil survival and effector functions. MSC from healthy donors, at very...
Uploaded on: May 13, 2023 -
2005 (v1)Publication
CCL3 (MIP-1alpha), a prototype of CC chemokines, is a potent chemoattractant toward human neutrophils pre-treated with GM-CSF for 15 min. GM-CSF-treated neutrophils migrate also to the selective CCR5 agonist CCL4 (MIP-1beta). CCL3- and CCL4-triggered migration of GM-CSF-primed neutrophils was inhibited by the CCR5 antagonist TAK-779....
Uploaded on: April 14, 2023 -
2006 (v1)Publication
Scanty information is available on chemokine receptor expression and function in childhood B-lineage acute lymphoblastic leukemia (ALL). Thirteen pro-B, 17 early pre-B, 12 pre-B, and 9 B-ALL/Burkitt lymphoma (BL) pediatric cases were tested for CXCR1 to CXCR5 and CCR1 to CCR7 expression. CXCR2, CXCR3, and CXCR4 were expressed in the majority of...
Uploaded on: April 14, 2023