P

PAIARDI G.

Last name: PAIARDI G.

2020 (v1)

Publication

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Rescuing defective CFTR applying a drug repositioning strategy based on computational studies, surface plasmon resonance and cell-based assays

D'Ursi P. Orro A. Urbinati C.

Cystic Fibrosis (CF) is caused by mutations (mainly F508del) of the cystic fibrosis transmembrane conductance regulator (CFTR). Current CF therapies are aimed at symptoms alleviation, calling for new drugs to rescue CFTR function. Hypothesis and objectives Drug repositioning is aimed at finding new applications for already marketed drugs,...

Uploaded on: April 14, 2023
2019 (v1)

Publication

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RESCUING DEFECTIVE CFTR APPLYING A DRUG REPOSITIONING STRATEGY

UGGERI, MATTEO Orro A. Urbinati C.

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Uploaded on: April 14, 2023
2019 (v1)

Publication

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Exploitation of a novel biosensor based on the full-length human F508del-CFTR with computational study, biochemical and biological assays for the characterization of a new Lumacaftor/Tezacaftor analogue.

D'Ursi P. Uggeri M. Urbinati C.

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Uploaded on: April 14, 2023