PAOLETTI G.

Introduction: Personalized/precision medicine has changed the vision of respiratory diseases. Asthma is now recognized as a heterogeneous disease with different pathogenic mechanisms, clinical course, and different responses to different treatments. Areas covered: According to this vision, the prescription of treatments has become more...

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Introduction: The precision medicine approach that is now mandatory for severe asthma management includes the use of novel biologic agents blocking specific immunological mechanisms that are responsible for disease phenotypes and endotypes: monoclonal antibodies blocking IgE, IL-5 and IL-4/IL-13 immunological pathways are so far available....