PAOLO CANEPA

Aminophosphonates were chosen for a first step functionalization of TiO2 grown on titanium, as they possess a phosphonate group on one end, that can be exploited for coupling with the oxide surface, and an amino group on the other end to enable further functionalization of the surface. The deposition of aminophosphonates with different chain...

By using AFM as a nanografting tool, we grafted micrometer-sized DNA platforms into inert alkanethiol SAMs. Tuning the grafting conditions (surface density of grafting lines and scan rate) allowed us to tailor the molecular density of the DNA platforms. Following the nanografting process, AFM was operated in the low perturbative Quantitative...

COVID-19 outbreak has spread rapidly, resulting in a worldwide critical health situation. RT-PCR is the standard method to diagnose SARS-CoV-2 infection, but faster and cheaper diagnostic tools are needed and continuously developing. We focus on an optical DNA-based biosensor, where DNA strands immobilized on gold are used to detect specific...

This concise survey delves into the capabilities of atomic force microscopy (AFM) for investigating the DNA/gold interface. It highlights how the precise control of the force applied by AFM enables its use as a nanolithography tool, allowing for localized sample modifications. The interface manipulation is functional to explore the DNA layer...

Porous transition metal oxides are widely studied as biocompatible materials for the development of prosthetic implants. Resurfacing the oxide to improve the antibacterial properties of the material is still an open issue, as infections remain a major cause of implant failure. We investigated the functionalization of porous titanium oxide...