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Last name: PARDO
First name: Gabriel
The radiologically isolated syndrome (RIS) represents the earliest detectable pre-clinical phase of multiple sclerosis (MS). This study evaluated the impact of therapeutic intervention in preventing first symptom manifestation at this stage in the disease spectrum.
Background and PurposeThe first randomized placebo-controlled therapeutic trial in radiologically isolated syndrome (RIS), ARISE, demonstrated that treatment with dimethyl fumarate (DMF) delayed the onset of a first clinical event related to CNS demyelination and was associated with a significant reduction in new and/or newly enlarging...
Spain is the second highest rice-producing country in the European Union, with approxi mately 105,000 ha used to grow this crop. The major rice-producing regions in Spain are Andalusia, Extremadura, Catalonia, and Valencia, followed by Aragon and Navarre. The main soil texture throughout Spanish rice areas is silty clay loam, with alkaline...
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