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PARISE , Amelia

Last name: PARISE

First name: Amelia

2015 (v1)

Publication

Metadata-only

Preparation, characterization and in vitro evaluation of sterically stabilized liposome containing a naphthalenediimide derivative as anticancer agent

Parise, Amelia Milelli, Andrea Tumiatti, Vincenzo

The aim of this study was to incorporate a new naphthalenediimide derivative (AN169) with a promising anticancer activity into pegylated liposomes to an extent that allows its in vitro and in vivo testing without use of toxic solvent. AN169-loaded liposomes were prepared using the thin-film hydration method and characterized for size,...

Uploaded on: April 14, 2023
2015 (v1)

Publication

Metadata-only

Tumor vascular targeted liposomal-bortezomib minimizes side effects and increases therapeutic activity in human neuroblastoma

Zuccari, Guendalina Milelli, Andrea Pastorino, Fabio

Neuroblastoma is a childhood cancer with poor long-term prognosis in advanced stages. A major aim in neuroblastoma therapy is to develop targeted drug delivery systems to ameliorate drug therapeutic index and efficacy. In this study, a novel bortezomib (BTZ) liposomal formulation was set-up and characterized. Since BTZ is freely permeable...

Uploaded on: March 27, 2023