PARKER , Drew

The current DTI-based markers of traumatic brain injury are able to capture affected WM in the brain, but missthe areas of crossing fibers and complex WM due to the simplicity of the model. In this work, we use a novelset of spherical-harmonics rotation invariant indices, recently proposed in the literature. We demonstrate thatthese 12...

In this work, we propose an edema-informed anatomically constrained tractography paradigm that enables reconstructing larger spatial extent of white matter bundles as well as increased cortical coverage in the presence of edema. These improvements will help surgeons maximize the extent of the resection while minimizing the risk of cogni-tive...

Objective. The use of non-invasive techniques for the estimation of structural brain networks (i.e. connectomes) opened the door to large-scale investigations on the functioning and the architecture of the brain, unveiling the link between neurological disorders and topological changes of the brain network. This study aims at assessing if and...

The analysis of connectomes and their associated network metrics forms an important part of clinical studies. These connectomes are based on tractography algorithms to estimate the structural connectivity between brain regions. However, tractography algorithms, are prone to false positive connections and this affects the quality of the...

Peritumoral edema prevents fiber tracking from diffusion tensor imaging (DTI). A free-water correction may overcome this drawback, as illustrated in the case of a patient undergoing awake surgery for brain metastasis. The anatomical plausibility and accuracy of tractography with and without free-water correction were assessed with functional...