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PARKS , Scott

Last name: PARKS

First name: Scott

March 5, 2018 (v1)

Journal article

Metadata-only

AKT1 restricts the invasive capacity of head and neck carcinoma cells harboring a constitutively active PI3 kinase activity

Brolih, Sanja Parks, Scott Vial, Valérie

Background: In mammals, the AKT/PKB protein kinase family comprises three members (AKT1–3). PI3-Kinase (PI3K), a key oncogene involved in a wide variety of cancers, drives AKT activity. Constitutive activation of the PI3K/AKT pathway has been associated with tumorigenic properties including uncontrolled cell proliferation and survival,...

Uploaded on: December 4, 2022