PARODI , Emanuele Luigi

In the last decades, many progress has been made in our understanding of kidney metabolism and transport of a wide amount of solutes. The purpose of this review is to highlight some issues of kidney metabolism which are still not completely understood and that are nonetheless implicated in the pathophysiology of chronic kidney disease. These...

Introduction: Early studies have shown that patients with chronic kidney disease (CKD) are able to maintain nitrogen balance despite significantly lower protein intake, but how and to what extent muscle protein metabolism adapts to a low-protein diet (LPD) or to a supplemented very LPD (sVLPD) is still unexplored. Methods: We studied muscle...