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PASTOR RAMÍREZ , Helena

Last name: PASTOR RAMÍREZ

First name: Helena

February 7, 2022 (v1)

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Síndrome LPAC secundario a deleción del exón 4 del gen ABCB4 en un paciente con hepatitis C

Fombuena, Blanca Ampuero Herrojo, Javier Álvarez, Luis

El síndrome LPAC (low-phospholipid-associated cholelithiasis syndrome) está asociado a mutaciones del gen ABCB4, que codifica la proteína MDR3, esencial en la secreción de fosfatidilcolina en las sales biliares. Este síndrome se caracteriza por una mayor prevalencia en mujeres, síntomas biliares en adultos jóvenes y excelente respuesta al ácido...

Uploaded on: March 25, 2023
October 11, 2022 (v1)

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Liver injury in non-alcoholic fatty liver disease is associated with urea cycle enzyme dysregulation

Gallego Durán, Rocío Ampuero Herrojo, Javier Pastor Ramírez, Helena

The main aim was to evaluate changes in urea cycle enzymes in NAFLD patients and in two preclinical animal models mimicking this entity. Seventeen liver specimens from NAFLD patients were included for immunohistochemistry and gene expression analyses. Three-hundred-and-eighty-two biopsy-proven NAFLD patients were genotyped for rs1047891, a...

Uploaded on: March 24, 2023