P
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Last name: PAVÓN PALACIO
First name: Juan José
Junta de Andalucía (Spain) / FEDER (EU), through the project Ref. P12-TEP-1401
Junta de Andalucía (Spain) / FEDER (EU), through the project Ref. P12-TEP-1401
Introducción: el titanio y algunas de sus aleaciones son considerados la mejor opción para fabricar implantes permanentes, debido a sus excelentes propiedades mecánicas y resistencia a la corrosión en el ambiente fisiológico, además de su buena biocompatibilidad y osteointegración. Objetivo: solucionar algunas de las limitaciones más...
One of the major limitations during titanium (Ti) implant osseointegration is the poor cellular interactions at the biointerface. In the present study, the combined effect of recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) and nanopatterned Ti6Al4V fabricated with Directed irradiation synthesis (DIS) is investigated in vitro. This...
Design, manufacture and validation of a simple and economic device that allows producing Ti cylinders with directed porosity applying the freeze-casting technique, and the study of the influence on the internal structure of the Ti porous samples when different materials are used for the vessel (alumina or Teflon).
Ministry of Economy and Innovation (Spain) project MAT2015-71284-P
Titanium implant failures are mainly related to stress shielding phenomenon and the poor cell interaction with host bone tissue. The development of bioactive and biomimetic Ti scaffolds for bone regeneration remains a challenge which needs the design of Ti implants with enhanced osseointegration. In this context, 4 types of titanium samples...
For the design of smart titanium implants, it is essential to balance the surface properties without any detrimental effect on the bulk properties of the material. Therefore, in this study, an irradiation-driven surface modification called directed irradiation synthesis (DIS) has been developed to nanopattern porousand"as-received"c.p. Tisur...
The stress shielding and the poor osseointegration in titanium implants are still problems to be resolved. In this context, this work proposes a balanced solution. Titanium samples were fabricated, with a porosity of 100-200 µm of pore size employing space-holder technique (50 vol. % NH4HCO3, 800 MPa at 1250 ºC during 2h under high vacuum...