2013 (v1)
Journal article
International audience
Uploaded on: December 4, 2022
P
B
Last name: PEI
First name: Bei
International audience
International audience
The shelterin proteins protect telomeres against activation of the DNA damage checkpoints and recombinational repair. We show here that a dimer of the shelterin subunit TRF2 wraps ∼ 90 bp of DNA through several lysine and arginine residues localized around its homodimerization domain. The expression of a wrapping-deficient TRF2 mutant, named...