2021 (v1)
Publication
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Uploaded on: January 31, 2024
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2019 (v1)Publication
Background: Steps towards the development of diagnostic criteria are needed for children with the radiologically isolated syndrome to identify children at risk of clinical demyelination. Objectives: To evaluate the 2005 and 2016 MAGNIMS magnetic resonance imaging criteria for dissemination in space for multiple sclerosis, both alone and with...
Uploaded on: April 14, 2023 -
2022 (v1)Publication
The radiologically isolated syndrome (RIS) represents the earliest detectable pre-clinical phase of multiple sclerosis (MS). This study evaluated the impact of therapeutic intervention in preventing first symptom manifestation at this stage in the disease spectrum.
Uploaded on: February 6, 2024 -
2024 (v1)Publication
Background and PurposeThe first randomized placebo-controlled therapeutic trial in radiologically isolated syndrome (RIS), ARISE, demonstrated that treatment with dimethyl fumarate (DMF) delayed the onset of a first clinical event related to CNS demyelination and was associated with a significant reduction in new and/or newly enlarging...
Uploaded on: October 21, 2024 -
2023 (v1)Publication
IMPORTANCE Radiologically isolated syndrome (RIS) represents the earliest detectable preclinical phase of multiple sclerosis (MS) punctuated by incidental magnetic resonance imaging (MRI) white matter anomalies within the central nervous system.OBJECTIVE To determine the time to onset of symptoms consistent with MS.DESIGN, SETTING, AND...
Uploaded on: February 14, 2024