PENNACCHIETTI F.

The post-synaptic area of the inhibitory synapse is characterized by sub-resolved clusters of the scaffold protein Gephyrin [1] that anchors GABAA receptor (GABAAR). Super-resolution techniques [2] based on Individual Molecule Localization (IML) [3] provide the capability to quantitatively study these subcellular structures, giving access to...

Single Layer Graphene (SLG) has emerged as a critically important nanomaterial due to its unique optical and electrical properties and has become a potential candidate for biomedical applications, biosensors, and tissue engineering. Due to its intrinsic 2D nature, SLG is an ideal surface for the development of large-area biosensors and, due to...

Bioavailability of photosensitizers for cancer photodynamic therapy is often hampered by their low solubility in water. Here, we overcome this issue by using the water-soluble protein apomyoglobin (apoMb) as a carrier for the photosensitizer hypericin (Hyp). The Hyp-apoMb complex is quickly uptaken by HeLa and PC3 cells at submicromolar...