PEREGO P.

The most common limitations of drug carriers, such as liposomes, are low Encapsulation Efficiency (EE), poor biocompatibility and drug degradation. Several techniques have been developed to overcome these problems; among these, Supercritical assisted Liposome formation (SuperLip) is a CO2 mediated technique for the production of liposomes at...

Valorization of agro-industrial waste by the extraction of bioactive molecules and their activity preservation by encapsulation is an open topic in process engineering. In this work, a combined approach for the recovery of antioxidants from spent coffee grounds by High Pressure and Temperature Extraction and the entrapment of extract into...

In recent years, the search for advanced packaging solutions has been oriented towards systems capable of extending the food shelf-life. One of the most interesting strategies is that of active packaging capable of releasing, in a controlled manner, antioxidant and antimicrobial agents. In this paper, the combined use of two promising...

The development of heterogeneous drug delivery systems leads to innovative strategies for targeted therapy of common pathologies, such as cancer, immunological and neurological disorders. Nowadays, it is possible to choose among a great variety of nanoparticles on the basis of the needs they have to satisfy. However, a candidate for the...

Over the previous years, the design, development, and potential application of nanocarriers in the medical field have been intensively studied for their ability to preserve drug properties, especially their pharmacological activity, and to improve their bioavailability. This work is a comparative study between two different types of...

Wastewater is one of the critical environmental problems worldwide. In this study, the circular economy concept was applied to winery wastewater that has been considered as a rich source of nutrients for growing edible microalgae to produce a high value protein product. To this end, Chlorella vulgaris and Arthrospira platensis were co-cultured....

Today, innovation in the food packaging field can be summed up in the concepts of active and intelligent packaging. These two concepts refer to systems capable of interacting and monitoring the storage conditions of packaged food products, allowing them to control their shelf-life and quality at any time to ensure safer products for consumers....

Cardiovascular diseases are the leading cause of mortality in the Western world. Among them, atherosclerosis represents one of the most common diseases in the modern society due to a common sedentary lifestyle, high-fat diet, and smoking. In the near future, a new approach could potentially improve the therapy of vascular pathologies, where to...

Apple processing industry can be improved by the valorization of its residues. Apple skins could be used for the recovery of high added value compounds for the formulation of new antioxidant products (dietary supplements, cosmetics, drugs). In this study, apple skins from Jonagold cultivar were selected as raw material for an optimization study...

Introduction: Benign metastasising leiomyoma refers to a type of lesion characterised by leiomyomatous alterations without any indication of malignancy. It presents as either a singular nodule or multiple nodules of proliferating smooth muscle cells and is generally found in the lungs of women who have undergone a hysterectomy. The purpose of...

Innovation in food packaging is mainly represented by the development of active and intelligent packing technologies, which offer to deliver safer and high-quality food products. Active packaging refers to the incorporation of active component into the package with the aim of maintaining or extending the product quality and shelf-life. The...

The interest in searching an alternative to the condition of "waste" for spent coffee is continuously growing in the scientific community. Indeed, the high content of polyphenols, caffeine, and tannins in this residue can potentially lead to pollution for water and soil, since they show toxicity for various plants, microorganisms, and aquatic...

Vanillin-loaded zein electrospun sub-micron fibers were produced by electrospinning and intended for food packaging applications. The effect of the addition of different vanillin concentrations on the properties of zein nanostructured membranes and the relationship with fiber morphology was studied. Results indicated that vanillin was loaded in...

Encapsulation of antibodies represents a significant advance to protect and deliver these therapeutics in a controlled manner, increasing the stability requested to cover the temporal gap between particle production and their administration. Furthermore, using encapsulation, extracellular, cell surface, and intracellular targets can be reached....