2021 (v1)
Publication
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Uploaded on: April 14, 2023
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2015 (v1)Publication
Neuroblastoma is a childhood cancer with poor long-term prognosis in advanced stages. A major aim in neuroblastoma therapy is to develop targeted drug delivery systems to ameliorate drug therapeutic index and efficacy. In this study, a novel bortezomib (BTZ) liposomal formulation was set-up and characterized. Since BTZ is freely permeable...
Uploaded on: March 27, 2023 -
2018 (v1)Publication
Targeted delivery of anticancer drugs with nanocarriers can reduce side effects and ameliorate therapeutic efficacy. However, poorly perfused and dysfunctional tumor vessels limit the transport of the payload into solid tumors. The use of tumor-penetrating nanocarriers might enhance tumor uptake and antitumor effects. A peptide containing a...
Uploaded on: April 14, 2023 -
2015 (v1)Publication
No description
Uploaded on: April 14, 2023 -
2023 (v1)Publication
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Uploaded on: February 11, 2024 -
2024 (v1)Publication
Background: Neuroblastoma (NB) represents the most frequent and aggressive form of extracranial solid tumor of infants. Although the overall survival of patients with NB has improved in the last years, more than 50% of high-risk patients still undergo a relapse. Thus, in the era of precision/personalized medicine, the need for high-risk NB...
Uploaded on: February 16, 2024