PICCO A.

Metabolic connectivity analysis of resting 18F-FDG PET is based on the assumption that brain regions whose metabolism is significantly correlated at rest are functionally associated and that the strength of the association is proportional to the magnitude of the correlation coefficient. Therefore, this method could be used to evaluate...

The use of biomarkers has been proposed for diagnosing Alzheimer's disease in recent criteria, but some biomarkers have not been sufficiently investigated to justify their routine clinical use. Here, we evaluate in a literature review the clinical validity of amyloid positron emission tomography (PET) imaging using a structured framework...