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PIFFERI , Carlo

Last name: PIFFERI

First name: Carlo

September 2017 (v1)

Journal article

Metadata-only

Chemobacterial Synthesis of a Sialyl-Tn Cyclopeptide Vaccine Candidate.

Richard, Emeline Pifferi, Carlo Fiore, Michele

A conjugatable form of the tumour-associated carbohydrate antigen sialyl-Tn (Neu5Ac-α-2,6-GalNAc) was efficiently produced in Escherichia coli. Metabolically engineered E. coli strains overexpressing the 6-sialyltransferase gene of Photobacterium sp. and CMP-Neu5Ac synthetase genes of Neisseria meningitidis were cultivated at high density in...

Uploaded on: February 28, 2023