2020 (v1)
Journal article
Phosphodiesterases (PDEs) form a superfamily of enzymes that catalyze the hydrolysis of cyclic nucleotides adenosine 3 5-cyclic monophosphate (cAMP) and guanosine 3 5-cyclic monophosphate (cGMP) to their inactive 5 monophosphates. cAMP plays a critical role as a second messenger in endocrine tissues, and activation of cAMP signaling has been...
Uploaded on: December 4, 2022