PITTALUGA , Anna

Synaptosomes are used to decipher the mechanisms involved in chemical transmission, since they permit highlighting the mechanisms of transmitter release and confirming whether the activation of presynaptic receptors/enzymes can modulate this event. In the last two decades, important progress in the field came from the observations that...

The existence of presynaptic, release-regulating N-methyl-D-aspartate receptors (NMDARs) in the central nervous system (CNS) has been long matter of discussion. Most of the reviews dedicated to support this conclusion preferentially focussed on the results from electrophysiological studies, paying scarce attention, if ever, to the data obtained...