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PLO , Isabelle

Last name: PLO

First name: Isabelle

December 2014 (v1)

Journal article

Metadata-only

p19INK4d Controls Hematopoietic Stem Cells in a Cell-Autonomous Manner during Genotoxic Stress and through the Microenvironment during Aging

Hilpert, Morgane Legrand, Céline Bluteau, Dominique

Hematopoietic stem cells (HSCs) are characterized by the capacity for self-renewal and the ability to reconstitute the entire hematopoietic compartment. Thrombopoietin maintains adult HSCs in a quiescent state through the induction of cell cycle inhibitors p57Kip2 and p19INK4d. Using the p19INK4d−/− mouse model, we investigated the role of...

Uploaded on: January 22, 2024