PORTAIS , Jean-Charles

Last name: PORTAIS

First name: Jean-Charles

September 1, 2014 (v1)

Conference paper

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Nouveaux éléments de chronologie relative et radionumérique à Cussac (Dordogne, France)

Goutas, N. Henry-Gambier, D. Katnecker, Évelyne

International audience

Uploaded on: February 22, 2023
September 1, 2014 (v1)

Conference paper

Metadata-only

Nouveaux éléments de chronologie relative et radionumérique à Cussac (Dordogne, France)

Goutas, N. Henry-Gambier, D. Katnecker, Évelyne

International audience

Uploaded on: December 4, 2022
2021 (v1)

Journal article

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Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis

Matias, Maria Yong, Carmen Foroushani, Amir

Suppressive regulatory T cell (Treg) differentiation is controlled by diverse immunometabolic signaling pathways and intracellular metabolites. Here we show that cell-permeable α-ketoglutarate (αKG) alters the DNA methylation profile of naive CD4 T cells activated under Treg polarizing conditions, markedly attenuating FoxP3+ Treg...

Uploaded on: December 3, 2022
July 5, 2017 (v1)

Journal article

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Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

Farge, Thomas Saland, Estelle de Toni, Fabienne

Chemotherapy-resistant human acute myeloid leukemia (AML) cells are thought to be enriched in quiescent immature leukemic stem cells (LSC). To validate this hypothesis in vivo, we developed a clinically relevant chemotherapeutic approach treating patient-derived xenografts (PDX) with cytarabine (AraC). AraC residual AML cells are enriched in...

Uploaded on: December 4, 2022

PORTAIS , Jean-Charles

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