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J

POUYSSEGUR , J.

Last name: POUYSSEGUR

First name: J.

June 7, 2007 (v1)

Journal article

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Selective inhibition of MEK1/2 reveals a differential requirement for ERK1/2 signalling in the regulation of HIF-1 in response to hypoxia and IGF-1.

Sutton, K. M. Hayat, S. Chau, N.-M.

The transcription factor hypoxia-inducible factor 1 (HIF-1) plays a pivotal role in tumour growth and progression, and HIF-1 is regulated through a number of signalling pathways. Here, we investigated the involvement of the mitogen-activated protein kinase (MAPK) signalling pathway in HIF-1 regulation. We found that overexpression of wild-type...

Uploaded on: December 4, 2022
2005 (v1)

Journal article

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HYPOXIA-INDUCIBLE FACTOR 1alpha IS A NEW TARGET OF MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR (MTF) IN MELANOMA CELLS

Busca, R. Berra, E. Gaggioli, C.

No description

Uploaded on: December 3, 2022
2005 (v1)

Journal article

Metadata-only

HYPOXIA-INDUCIBLE FACTOR 1alpha IS A NEW TARGET OF MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR (MTF) IN MELANOMA CELLS

Busca, R. Berra, E. Gaggioli, C.

No description

Uploaded on: October 11, 2023