R. AUGUGLIARO

Last name: R. AUGUGLIARO

2001 (v1)

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NTB-A, a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked lymphoproliferative disease.

BOTTINO, CRISTINA M. Falco S. Parolini

In humans, natural killer (NK) cell function is regulated by a series of receptors and coreceptors with either triggering or inhibitory activity. Here we describe a novel 60-kD glycoprotein, termed NTB-A, that is expressed by all human NK, T, and B lymphocytes. Monoclonal antibody (mAb)-mediated cross-linking of NTB-A results in the induction...

Uploaded on: April 14, 2023
1998 (v1)

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NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis.

M. Vitale BOTTINO, CRISTINA SIVORI, SIMONA

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Uploaded on: March 31, 2023
1999 (v1)

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Molecular and functional characterization of IRp60, a member of the immunoglobulin superfamily that functions as an inhibitory receptor in human NK cells.

CANTONI, CLAUDIA BOTTINO, CRISTINA R. Augugliaro

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Uploaded on: April 14, 2023
1999 (v1)

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Identification and molecular characterization of NKp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells.

D. Pende MORETTA, LORENZO A. Pessino

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Uploaded on: April 14, 2023
2003 (v1)

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CD59 is physically and functionally associated with natural cytotoxicity receptors and activates human NK cell-mediated cytotoxicity

MARCENARO, EMANUELA R. Augugliaro M. Falco

Triggering of cytotoxicity in human NK cells is induced by the combined engagement of several triggering receptors. These include primary receptors such as NKG2D and the natural cytotoxicity receptors (NCR) NKp30, NKp46 and NKp44, while other molecules, including 2B4, NTB-A and NKp80, function as co-receptors. As reported in the present study,...

Uploaded on: April 14, 2023
2012 (v1)

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Melanoma cells become resistant to NK-cell-mediated killing when exposed to NK-cell numbers compatible with NK-cell infiltration in the tumor

M. Balsamo W. Vermi M. Parodi

During the past few years, a number of studies reported that different melanoma cell lines could be extensively lysed in vitro by IL-2-activated NK cells at appropriate effector/target ratios. Here, we show, by histological evaluation of different melanoma lesions, that NK/target-cell ratios compatible with those allowing efficient melanoma...

Uploaded on: March 31, 2023

R. AUGUGLIARO

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