RAVERA , Silvia

More than any other organs, brain energy demand is entirely dependent on glucose catabolism through the oxidative phosphorylation (OXPHOS). Glucose is the major cerebral energy substrate in the nervous system (NS). Ketone bodies can be utilized as an additional substrate, but in any case, neurons critically depend on oxygen supply. This sounds...

Nervous system is a great oxygen consumer, but the site of oxygen absorption has remained elusive. Four proteomic studies have shown that the respiratory complexes I to V may be expressed in isolated myelin. Myelin is an outgrowth of glial cells, surrounding many axons in multiple spires both in peripheral and central nervous system. Recent...

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The eVects of extremely low frequency electromagnetic Welds of 75Hz were studied on diVerent membrane-associated enzymes. Only the activities of three enzymes out of seven exposed to the Weld decreased approximately of about 54–61% with Weld amplitudes above a threshold of 73–151 T depending on the enzyme. The same Weld had no eVect on the...

The combinatorial peptide ligand library (CPLL) in association with mass spectrometry (MS) can greatly enhance the dynamic range of the analysis of low and very low-abundance proteins constituting the vast majority of species in any sample. When compared with untreated samples, the increment in detection of low-abundance species appears to be...