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REGGIANI , Francesco

Last name: REGGIANI

First name: Francesco

2022 (v1)

Publication

Metadata-only

In uveal melanoma Gα-protein GNA11 mutations convey a shorter disease-specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than Gα-protein GNAQ mutations

Piaggio, Francesca Croce, Michela Reggiani, Francesco

Background and aim of the study: Mutations in the G alpha-genes GNAQ and GNA11 are found in 85-90% of uveal melanomas (UM). Aim of the study is to understand whether the mutations in both genes differentially affect tumor characteristics and outcome and if so, to identify potential mechanisms.Methods: We analyzed the association between GNAQ...

Uploaded on: February 14, 2024