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REINA , José Juan

Last name: REINA

First name: José Juan

July 13, 2022 (v1)

Publication

Metadata-only

Synthesis and in vitro inhibition properties of siRNA conjugates carrying glucose and galactose with different presentations

Aviñó, Anna Ocampo, Sandra M. Lucas Rodríguez, Ricardo

Oligoribonucleotide conjugates and the corresponding siRNA duplexes against tumor necrosis factor carrying one, two, or four glucose and galactose residues at the 5'-end have been prepared using phosphoramidite chemistry. Carbohydrate-modified siRNA duplexes have similar inhibitory properties than unmodified RNA duplexes in HeLa cells...

Uploaded on: March 25, 2023